Police are at the scene of a serious crash at the intersection of Tay and Clyde Streets, Invercargill.

Emergency services were alerted to a single vehicle crash shortly after 5am.

Three people haver a range of injuries and have been transported to hospital.

The Serious Crash Unit has been advised.

The road remains closed between Forth and Spey Streets.

An alterative route is now in place.

For northbound traffic, turn left on to Forth Street, right on to Liddel Street, continue on to Leven Street and back on to State Highway 6. For southbound traffic, turn left on to Spey Street, right on to Kelvin Street, continue on to Nith Street , turn right on to Forth Street, then back on to State Highway 1.

Police advise it could be for some time until the scene examination is completed and have asked motorists to avoid the area.