An Invercargill house has been significantly damaged this morning after being hit by a police vehicle that was attempting to stop a fleeing driver.

Police were called to a family harm matter in Invercargill shortly after 10am. After threatening people at an address a man has then fled in a vehicle.

Acting area commander Inspector Mike Bowman said that while responding to the incident police located the vehicle near Grasmere and attempted to stop it by laying road spikes.

The fleeing driver has avoided the road spikes and continued driving towards Invercargill.

"Police patrols continued to follow the fleeing driver towards the Windsor area," he said . "The fleeing driver has then collided with a police car and as a result of this crash the police vehicle has hit a house causing significant damage."

No-one was seriously injured in the incident.

The fleeing driver, a male, was arrested at the scene.

"Police would like to hear form any witnesses to the crash or anyone who saw the fleeing driver travelling in a red Mitsubishi ute between Grasmere and Windsor between 10am and 10.45am."

Police inquiries are continuing into both the family harm incident and the crash.

Anyone with information is asked to contact Invercargill Police on 03 211 0400.